SWSLHD CLIN Libraries have created a LibGuide for all medical exams. Check it out!
Library staff can assist you with:
Contact or visit your local CLIN Library to find out more about our full range of services and for assistance with your research project.
This library guide is to help support you in your professional development. Please give us feedback so we can improve this list in the future.
If you have any questions, please contact the Clinical Library on 9722 8250 or email
SWSLHD-BankstownLibrary@health.nsw.gov.au or visit us Monday to Fridays, 8.30am - 5.00pm (closed Wednesday afternoons)
“One Spot Rapid Pleurodesis- Thoracoscopic management of
malignant pleural effusion.”
Banka, R., et al. (2020). "Multidisciplinary approaches to the management of malignant pleural effusions: a guide for the clinician." Expert Review of Respiratory Medicine 14(10): 1009-1018.
https://www.tandfonline.com/doi/abs/10.1080/17476348.2020.1793672
Introduction: Malignant pleural effusion (MPE) is a complication of advanced cancer, associated with significant mortality and morbidity. This entity is commonly treated by respiratory physicians, oncologists, and thoracic surgeons. There have been various randomized clinical trials assessing the relative merits of chest drain pleurodesis, indwelling pleural catheters, treatment of septated MPEs, the use of thoracoscopy and pleurodesis and pleurodesis through IPCs in the past decade which have addressed some key areas in the management of MPEs, with an increasing focus on patient related outcome. Areas covered: In this review, we examine and review the literature for management strategies for MPEs and discuss future directions. A detailed search of scientific literature and clinical trial registries published in the past two decades was undertaken. Expert opinion: Tremendous progress has been made in management of MPE in the past decade and current strategy involves patient preference along with local expertise that is available.
Bashour, S. I., et al. (2022). "Update on the diagnosis and management of malignant pleural effusions." Respiratory Medicine 196: 106802. https://www.sciencedirect.com/science/article/pii/S0954611122000671
Roughly 150,000 malignant pleural effusions (MPE) are diagnosed in the United States each year. The majority of cases are caused by lung and breast cancer, and since MPE represents advanced disease, the prognosis is generally poor. In this article we review the pathophysiology, epidemiology, and prognosis of MPE. We then discuss the approach to diagnosis of MPE including the role of imaging, pleural fluid analysis, and medical thoracoscopy. Current management strategies for symptomatic MPE include repeated thoracentesis for patients with very limited life expectancy as well as more definitive procedures such as chemical pleurodesis, tunneled indwelling pleural catheters, and novel combined approaches. The choice of intervention is guided by the efficacy, local expertise, and risk, as well as patient factors and preferences.
Foo, C. T., et al. (2021). "Ambulatory Thoracoscopic Pleurodesis Combined With Indwelling Pleural Catheter in Malignant Pleural Effusion." Frontiers in Surgery 8.
https://www.frontiersin.org/journals/surgery/articles/10.3389/fsurg.2021.738719/full
Background and Objective: Malignant pleural effusion (MPE) often results in debilitating symptoms. Relief of dyspnoea and improvement in quality of life can be achieved with either talc pleurodesis or insertion of an indwelling tunneled pleural catheter (IPC). The former requires a lengthy hospital stay and the latter is associated with lower pleurodesis rates. In response to limited hospital bed capacity, we developed a pragmatic approach in managing MPE by combining thoracoscopic talc poudrage and insertion of IPC into a single day case procedure. We present data on the safety and efficacy of this approach. Methods: Patients who had undergone the abovementioned procedure between 2017 and 2020 were analyzed. Demographic data, hospital length of stay (LOS), histological diagnosis, rates of pleurodesis success and procedural related complications were collated. Patients were followed-up for 6 months. Results: Forty-five patients underwent the procedure. Mean age was 68.5 ± 10.4 years and 56% were male. Histological diagnosis was achieved in all cases. 86.7% of patients were discharged on the day of the procedure. Median LOS was 0 (IQR 0–0) days. Successful pleurodesis was attained in 77.8% at 6-month follow-up. No procedure related deaths or IPC related infections were recorded. Conclusion: Ambulatory thoracoscopic poudrage and IPC insertion is a safe and effective option in the management of MPE. All patients received a definitive pleural intervention with 77.8% pleurodesis success at 6-months and majority of them discharged on the same day. Future randomized trials are required to confirm these findings.</p>
Jacobs, B., et al. (2022). "Diagnosis and Management of Malignant Pleural Effusion: A Decade in Review." Diagnostics 12(4): 1016. https://www.mdpi.com/2075-4418/12/4/1016
Malignant pleural effusion (MPE) is a common complication of thoracic and extrathoracic malignancies and is associated with high mortality. Treatment is mainly palliative, with symptomatic management achieved via effusion drainage and pleurodesis. Pleurodesis may be hastened by administering a sclerosing agent through a thoracostomy tube, thoracoscopy, or an indwelling pleural catheter (IPC). Over the last decade, several randomized controlled studies shaped the current management of MPE in favor of an outpatient-based approach with a notable increase in IPC usage. Patient preferences remain essential in choosing optimal therapy, especially when the lung is expandable. In this article, we reviewed the last 10 to 15 years of MPE literature with a particular focus on the diagnosis and evolving management.
Therapeutic Guidelines - Respiratory.
Available via CIAP (login required for home use).
BMJ Best Practice. Available via CIAP (login required for home use).